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IGF-1 DES 1mg — research compound

IGF-1 DES 1mg

Growth

Background

IGF-1 DES(1-3) is a truncated variant of IGF-1 LR3 — three amino acids shorter, at 67 residues instead of LR3's 83. That shorter N-terminus actually increases its binding affinity at the IGF-1 receptor roughly tenfold, but it clears the body in 20-30 minutes versus LR3's 20-30 hours, making its action far more localized and short-lived than LR3's extended systemic exposure.

Not FDA-approved; sold for research use only.

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Frequently asked questions

Is IGF-1 DES the same as IGF-1 LR3?+

No — same parent hormone, different modification. DES removes three N-terminal amino acids for a short, potent, localized effect; LR3 adds amino acids for a long, systemic one.

Which is more potent?+

DES has higher intrinsic receptor affinity, but LR3's much longer half-life gives it more total systemic exposure over time. "More potent" depends on which effect (peak local activity vs. sustained circulating levels) is being measured.

Is IGF-1 DES FDA-approved?+

No. It is not an approved drug in any form and is sold for research use only.

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