
Adipotide (FTPP, Fat-Targeted Proapoptotic Peptide) was developed at MD Anderson Cancer Center and the Barshop Institute for Longevity and Aging Studies. Rather than acting on hormones or appetite, it's designed to trigger apoptosis specifically in the blood vessels supplying white adipose tissue — starving fat cells of blood flow rather than signaling the body to burn them.
No. It has never been approved by the FDA or any other regulatory body and is sold strictly for research use.
The most notable data is a study in obese rhesus monkeys, where treated animals lost weight and showed improved insulin sensitivity within a month, with imaging confirming reduced white adipose tissue. Human trial data is not established.
Those work through appetite and metabolic hormone receptors. Adipotide's proposed mechanism is structural — collapsing the microvasculature that feeds fat tissue, causing localized cell death rather than a systemic metabolic shift.
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